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Updated: Jul 17, 2026

Cecal Ligation and Puncture-induced Sepsis as a Model To Study Autophagy in Mice
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OTUD1通过促进HK2线粒体的释放来驱动微质皮质死,从而加剧败血症相关的脑病变

Guoqing Jing1, Hailong Gong1, Han Wang2,3

  • 1Research Centre of Anesthesiology and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, Hubei Province, China.

Journal of neuroinflammation
|June 11, 2025
PubMed
概括

卵巢瘤二基因酶1 (OTUD1) 通过促进微质质质灭菌,驱动了败血症相关的脑病变 (SAE). 针对OTUD1-hexokinase 2 (HK2) 轴可能会减轻SAE诱导的认知缺陷.

关键词:
在HK2HK2微质细胞中的微质细胞在OTUD1中,我们可以使用OTUD1.热灭菌的发生.在SAE的SAE.

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