在鼻炎中嗅觉功能障碍的机制,诊断和治疗
Hai Zhu1, Siyuan Qu1, Mengdan Gong1
1Department of Otorhinolaryngology-Head and Neck Surgery, The Affiliated Lihuili Hospital, Ningbo University, Ningbo, 315040, Zhejiang, China.
慢性鼻炎 (CRS) 的嗅觉功能障碍显著影响生活质量. 传统的嗅觉训练显示出作为这种常见的CRS症状的非侵入性治疗的希望.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 神经学 神经学
- 免疫学 免疫学 免疫学
背景情况:
- 嗅觉功能障碍影响60-80%的慢性鼻炎 (CRS) 患者.
- 这种症状严重影响生活质量,并增加安全风险.
研究的目的:
- 审查CRS相关的嗅觉功能障碍的流行病学,风险因素和病原性.
- 分析嗅觉评估方法,诊断和治疗策略以及未来的研究方向.
主要方法:
- 关于CRS相关的嗅觉功能障碍的综合文献综述.
- 分析病理生理学,临床特征和治疗策略.
- 嗅觉评估工具的比较和治疗疗效的评估.
主要成果:
- 病原发生涉及导电性问题,炎症和嗅球缩.
- 手术和药物治疗的疗效有所变化.
- 嗅觉训练是一个有前途的非侵入性治疗选择.
结论:
- 嗅觉功能障碍与CRS中的2型炎症有关.
- 需要对嗅球体积变化和干细胞转换进行进一步的研究.
- 最佳的皮质类固醇路径和长期的外科疗效需要研究.
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