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探索阿玛兰的纳米粒子制造能力及其生物功能

Sumathy Rengarajan¹, Renuga Devi Navaneethan², S Alagendran³

¹Department of Biotechnology, Valliammal College for Women, Chennai, Tamil Nadu, India.

Luminescence : the journal of biological and chemical luminescence

|June 12, 2025

概括

从Amaranthus spinosus树叶提取物中合成的银纳米颗粒显示出增强的抗菌,抗氧化和抗癌特性. 这些环保纳米颗粒为各种生物医学应用提供了强大的治疗潜力.

科学领域:

纳米技术纳米技术
药理学药理学是指药理学的学科.
药用化学医学化学

背景情况:

刺 (Amaranthus spinosus) 是一个公认的药用植物.
银纳米粒子 (AgNPs) 具有多种生物活动.
纳米颗粒的绿色合成提供了一个环保的方法.

研究的目的:

为了合成银纳米颗粒 (AgNPs),使用阿玛兰树 (Amaranthus spinosus) 叶提取物.
为了描述合成的AgNPs.
评估AgNPs的抗菌,抗氧化和抗癌潜力.

主要方法:

绿色合成AgNPs使用甲醇叶提取物的A. spinosus.
使用UV-Vis光谱,FTIR,SEM和XRD进行表征.
在体外评估抗微生物活性对克莱布西拉肺炎.
抗氧化剂测试 (DPPH,基清除,降低功率).
在体外抗癌测定对HT-29结直肠癌细胞使用AO/EtBr和DAPI染色.

主要成果:

通过颜色变化和光谱分析证实了合成.
XRD证实了晶体性质;SEM显示球形纳米粒子<100 nm.
AgNPs显示出强大的抗微生物活性,可以对抗Klebsiella pneumoniae.
AgNPs表现出显著的自由基清除和降低功率,超过了植物提取物.
在HT-29细胞中,AgNPs诱导了度依赖的细胞毒性和亡.

结论:

衍生于Amaranthus spinosus的AgNP具有增强的抗菌,抗氧化和抗癌特性.
这种环保的合成方法可以产生稳定有效的纳米粒子.
这些AgNP显示出生物医学应用的重大前景.

关键词:

农业农产物种植者 (AgNPs) 是一个.标签: 美国美国 HT-29 这是一种抗癌药物.抗氧化剂是一种抗氧化剂.绿色合成是一种绿色合成.

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