在急性缺血性中风中使用RED 43吸入导管进行远端血管吸入 (DIVA研究):国际多中心体验
Vinicius Carraro do Nascimento1, Permesh Singh Dhillon1,2, Laetitia de Villiers1
1Department of Interventional Neuroradiology, Gold Coast University Hospital, Queensland, Australia.
概括
在急性缺血性中风患者中,RED 43导管安全有效地治疗了中等血管封闭,实现了高的再通道率. 这种新的装置对机械血栓切除手术非常有前途.
科学领域:
- 神经学 神经学
- 干预性神经放射学 干预性神经放射学
- 血管外科 血管外科
背景情况:
- 机械血栓切除术 (MT) 对来自中等血管封闭 (MeVOs) 的急性缺血性中风 (AIS) 至关重要.
- 针对MeVO的最佳再通道化技术仍在调查中.
- 远端再注射导管RED 43是一种用于MeVO治疗的新型装置.
研究的目的:
- 评估RED 43吸入导管用于治疗MeVOs的有效性和安全性.
- 评估程序结果,包括导航,再通道率和临床结果.
- 分析与RED 43导管相关的安全并发症.
主要方法:
- 连续发生的AIS病例的回顾性审查,MeVO用RED 43导管治疗.
- 从澳大利亚和英国的四个中风中心收集的数据 (2023年4月 - 2024年6月).
- 对程序结果 (eTICI 2c-3,FPE),90天的mRS和安全并发症的分析.
主要成果:
- 100%成功地通过RED 43导管导航到目标阻塞部位.
- 77%的患者在脑梗塞中实现了最终扩展的血栓溶解 (eTICI) 2c-3再通道化.
- 60.8%的第一通效应 (FPE) eTICI 2c-3实现; 67.1%的修改兰金度量 (mRS) ≤2在90天.
- 没有过程内并发症;4.1%的症状内出血和19%的90天死亡率.
结论:
- 红色43远端吸入导管是安全有效的治疗MeVOs在AIS患者.
- 该设备有助于获得良好的技术和临床结果.
- 未来的研究应该对MeVOs的MT技术进行比较,以优化重新道化速度和完整性.
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