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运用流氧葡萄糖正子发射断层扫描计算机断层扫描在胆道癌症中的应用进展

Jia-Xin Yin¹, Xin Fan¹, Qiao-Liang Chen¹

¹Department of Nuclear Medicine, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210008, Jiangsu Province, China.

World journal of hepatology

|June 12, 2025

概括

18F-FDG PET/CT成像技术推进了胆道癌 (BTC) 的检测和分期. 最近的进展包括定量分析,放射学和深度学习,以改善肝脏内胆管癌 (ICC) 的预后和诊断.

科学领域:

在瘤学瘤学.
医疗成像医学成像
核医学就是核医学.

背景情况:

胆道癌 (BTC) 涵盖了各种各样的,具有不良预后的侵袭性癌症,尤其是肝内胆道癌 (ICC).
传统的成像技术在检测微转移和反复的BTC病变方面存在局限性.
18F-FDG PET/CT提供了对瘤代谢,转移和分子特征的非侵入性评估.

研究的目的:

在过去十年中,审查18F-FDG PET/CT对胆道癌 (BTC) 的研究进展,重点是过去三年.
突出转向量化成像和BTC管理中的新应用的转变.
用先进的成像技术来总结预测基因表达,预后和差异诊断方面的进展.

主要方法:

审查最近的科学文献,重点是BTC中的18F-FDG PET/CT.
分析使用定量成像指标,放射学和深度学习的研究.
包括对PET/磁共振成像 (MRI) 应用的研究.

主要成果:

18F-FDG PET/CT对于BTC的临床分期,治疗评估和预后预测至关重要.
重要的突破包括对代谢异质性的定量分析和预测ICC中的基因表达.
放射学和深度学习在ICC中的预后预测和差异诊断方面表现有前途.

结论:

18F-FDG PET/CT已经发展成为全面BTC评估的关键工具.
新兴的定量和人工智能驱动的方法正在增强诊断和预后能力.
PET/MRI为BTC成像研究提供了有价值的未来方向.

关键词:

胆道癌是一种胆道癌症.化氧葡萄糖正子辐射断层扫描.pozitron 辐射断层扫描计算机断层扫描计算机断层扫描定子发射断层扫描磁共振成像磁共振成像阳位子放射药品阳位子放射药品无线电学 (Radiomics) 是一种辐射学.

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