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Updated: Jun 13, 2025

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在胰腺瘤发生过程中,分子动力学推动了KRAS突变体之间的表型差异

Adrien Grimont, David J Falvo, Whitney J Sisso

    bioRxiv : the preprint server for biology
    |June 12, 2025
    PubMed
    概括

    不同的KRAS突变启动了不同的胰腺癌轨迹. 克拉斯G12D驱动瘤启动,而克拉斯G12R/V显示持续瘤生长的缺陷由于信号通路变化.

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