相关实验视频

Updated: Jun 13, 2025

Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions
07:12

Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions

Published on: July 17, 2020

6.2K

化学捕获的diazo代谢产物揭示了生物合成氧化氧化

Katarina Pfeifer, Devon Van Cura, Kelvin J Y Wu

    bioRxiv : the preprint server for biology
    |June 12, 2025
    PubMed
    概括

    研究人员开发了一种新的选方法,以发现反应性微生物代谢物,特别是二化合物. 这种方法确定了两种新型天然产品和一种独特的酶,Dob3,具有生物催化潜力.

    更多相关视频

    Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides CHIPS06:34

    Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides CHIPS

    Published on: June 20, 2014

    13.8K
    Continuous Flow Chemistry: Reaction of Diphenyldiazomethane with p-Nitrobenzoic Acid07:06

    Continuous Flow Chemistry: Reaction of Diphenyldiazomethane with p-Nitrobenzoic Acid

    Published on: November 15, 2017

    11.4K

    相关概念视频

    Aryldiazonium Salts to Azo Dyes: Diazo Coupling01:11

    Aryldiazonium Salts to Azo Dyes: Diazo Coupling

    The reaction of weakly electrophilic aryldiazonium (also called arenediazonium) salts with highly activated aromatic compounds leads to the formation of products with an —N=N— link, called an azo linkage. This reaction, presented in Figure 1, is known as diazo coupling and occurs without the loss of the nitrogen atoms of the aryldiazonium salt. Highly activated aromatic compounds such as phenols or arylamines favor the diazo coupling reaction. The coupling generally occurs at the...
    2.9K
    Diazonium Group Substitution: –OH and –H01:19

    Diazonium Group Substitution: –OH and –H

    Nitrous acid, a weak acid, is prepared in situ via the reaction of sodium nitrite with a strong acid under cold conditions. This nitrous acid prepared in situ reacts with primary arylamines to form arenediazonium salts. Such reactions are known as diazotization reactions. As shown in Figure 1, the formation of arenediazonium salts begins with the decomposition of nitrous acid in an acidic solution to give nitrosonium ions.
    2.7K
    Oxidation of Alkenes: Syn Dihydroxylation with Osmium Tetraoxide02:44

    Oxidation of Alkenes: Syn Dihydroxylation with Osmium Tetraoxide

    Alkenes are converted to 1,2-diols or glycols through a process called dihydroxylation. It involves the addition of two hydroxyl groups across the double bond with two different stereochemical approaches, namely anti and syn. Dihydroxylation using osmium tetroxide progresses with syn stereochemistry.
    9.9K
    Carboxylic Acids to Methylesters: Alkylation using Diazomethane01:33

    Carboxylic Acids to Methylesters: Alkylation using Diazomethane

    Carboxylic acids react with diazomethane in an ether solvent via alkylation at the carboxylate oxygen atom to give methyl esters of the corresponding acid with excellent yields.
    2.1K
    Aldehydes and Ketones to Alkanes: Wolff–Kishner Reduction01:09

    Aldehydes and Ketones to Alkanes: Wolff–Kishner Reduction

    Wolff–Kishner reduction involves converting aldehydes and ketones to alkanes using hydrazine and a base. The reaction converts a carbonyl group to a methylene group. The method was independently discovered by N. Kishner in 1911 and L. Wolff in 1912. The reduction is carried out in high-boiling solvents such as ethylene glycol and diethylene glycol because heat is required to deprotonate the N–H proton in one of the reaction steps.                                       ...
    4.4K
    1° Amines to Diazonium or Aryldiazonium Salts: Diazotization with NaNO2 Mechanism01:37

    1° Amines to Diazonium or Aryldiazonium Salts: Diazotization with NaNO2 Mechanism

    Nitrous acid is a relatively weak and unstable acid prepared in situ by the reaction of sodium nitrite and cold, dilute hydrochloric acid. In an acidic solution, the nitrous acid undergoes protonation when it loses water to form a nitrosonium ion—an electrophile. Nitrous acid reacts with primary amines to give diazonium salts. The reaction is called diazotization of primary amines.
    3.7K