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Updated: Jun 13, 2025

In Vitro Analysis of E3 Ubiquitin Ligase Function
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通过ASB9-CUL5 Ubiquitin Ligase进行的基基化机制

Calvin P Lin, Nathan H Lee, Francis X Alipranti

    bioRxiv : the preprint server for biology
    |June 12, 2025
    PubMed
    概括

    安基林和SOCS盒子蛋白9 (ASB9) E3结合酶复合体针对特定的组织蛋白 (H3和H4)进行降解. 这项研究揭示了在没有辅助酶的情况下的ASB9-Cullin 5酶活性,突出了新的无处不在化途径.

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