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Updated: Jun 13, 2025

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成熟星体细胞中PTBP1的枯竭显示出明显的剪接变化,没有神经元特征

Min Zhang, Naoto Kubota, David Nikom

    bioRxiv : the preprint server for biology
    |June 12, 2025
    PubMed
    概括

    仅仅针对PTBP1对天体细胞到神经元重编程是不够的. 星球细胞中PTBP1的损失会改变结合,但不会诱导神经元基因表达,从而挑战治疗策略.

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