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Updated: Jun 13, 2025

Efficient and Scalable Production of Full-length Human Huntingtin Variants in Mammalian Cells using a Transient Expression System
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Efficient and Scalable Production of Full-length Human Huntingtin Variants in Mammalian Cells using a Transient Expression System

Published on: December 10, 2021

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在亨廷顿病中,表观遗传机制控制了细胞类型特定的身体扩张和毒性

Matthew Baffuto, Kert Mätlik, Isaac Ilyashov

    bioRxiv : the preprint server for biology
    |June 12, 2025
    PubMed
    概括

    亨廷顿病 (HD) 涉及影响大脑细胞的基因变化. 这项研究揭示了驱动基因失调的表观遗传机制,并为HD的进展提供了一个模型.

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