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Updated: Jun 13, 2025

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G1和G2 ApolipoproteinL1通过聚胺通路调节巨细胞炎症和脂质积累

Esther Liu, Matthew Wright, Andrew O Kearney

    bioRxiv : the preprint server for biology
    |June 12, 2025
    PubMed
    概括

    Apolipoprotein L1 (APOL1) 的G1和G2变体通过增加脂质积累和改变新陈代谢来促进巨细胞的炎症. 抑制精氨酸合成可以减少这些由APOL1驱动的炎症效应.

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