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Updated: May 7, 2026

Analysis of Simian Immunodeficiency Virus-specific CD8+ T-cells in Rhesus Macaques by Peptide-MHC-I Tetramer Staining
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Analysis of Simian Immunodeficiency Virus-specific CD8+ T-cells in Rhesus Macaques by Peptide-MHC-I Tetramer Staining

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选择性繁殖 rhesus 的基因组遗产用于与艾滋病毒/艾滋病相关的研究

M M Lyke, A Bagwell, D Newman

    bioRxiv : the preprint server for biology
    |June 12, 2025
    PubMed
    概括

    针对 rhesus 的有针对性的繁殖策略成功地减少了与 Simian Immunodeficiency Virus (SIV) 抗性主要基因相容性复合体 (MHC) 杂型,同时保持了遗传多样性. 这提高了它们在艾滋病毒/艾滋病研究中的实用性,因为它们提高了对疾病的抵抗力.

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    相关概念视频

    Exon Recombination02:32

    Exon Recombination

    The evolution of new genes is critical for speciation. Exon recombination, also known as exon shuffling or domain shuffling, is an important means of new gene formation. It is observed across vertebrates, invertebrates, and in some plants such as potatoes and sunflowers. During exon recombination, exons from the same or different genes recombine and produce new exon-intron combinations, which might evolve into new genes. 
    Exon shuffling follows “splice frame rules.” Each exon has three reading...