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Updated: Jun 13, 2025

Enrichment and Characterization of the Tumor Immune and Non-immune Microenvironments in Established Subcutaneous Murine Tumors
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在批量瘤样本中评估体质突变异位基因的丰富表达时的混因素

Kohei Hagiwara, Andrew Thrasher, Nadezhda V Terekhanova

    bioRxiv : the preprint server for biology
    |June 12, 2025
    PubMed
    概括

    由于瘤纯度,等位基特异性表达 (ASE) 分析可能会产生误导性. 这项研究引入了一种用于纠正混因素的模型,使用RNA测序数据改进体质突变检测.

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    Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies

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