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Updated: Jun 13, 2025

Co-immunoprecipitation Assay Using Endogenous Nuclear Proteins from Cells Cultured Under Hypoxic Conditions
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Published on: August 2, 2018

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HIF异构体的上下文依赖性变异性影响与宏分子和小分子伙伴的相互作用

Joseph D Closson, Xingjian Xu, Meiling Zhang

    bioRxiv : the preprint server for biology
    |June 12, 2025
    PubMed
    概括

    缺氧诱导因子 (HIFs) 在扩展的DNA上形成新的"异构体的二分体" (DoHD) 复合体,影响连接体和协同激活体的结合. 这些发现揭示了HIF在细胞反应中的复杂调节机制.

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