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Updated: Jun 13, 2025

Generation of Human Alloantigen-specific T Cells from Peripheral Blood
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Generation of Human Alloantigen-specific T Cells from Peripheral Blood

Published on: November 21, 2014

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以HLA-DQ单体为基础的丰富全活性CD4T细胞

Zhuldyz Zhanzak, Davide Cina, Xueqiong Zhang

    bioRxiv : the preprint server for biology
    |June 12, 2025
    PubMed
    概括

    这项研究开发了一种新方法来检测针对捐赠者HLA-DQ抗原的特定T细胞. 这一进展有助于了解移植排斥和改善移植的存活率.

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    T Cell Activation and Clonal Selection01:22

    T Cell Activation and Clonal Selection

    T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
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