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Updated: Jun 13, 2025

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母亲维生素C缺乏和遗传风险因素通过DNA甲基化失调导致先天性缺陷

Bernard K van der Veer, Colin Custers, Wannes Brangers

    bioRxiv : the preprint server for biology
    |June 12, 2025
    PubMed
    概括

    孕产妇维生素C (VitC) 缺乏会导致发育迟缓和出生缺陷的小鼠无法合成VitC. 在怀孕期间减少VitC摄入量可能导致DNA高甲基化和神经管缺陷,影响胎儿表观基因组发育.

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