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Updated: Jun 14, 2025

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GM@mTG-V微球通过重建IVD生物力学和炎症微环境来促进NP再生

Rong Gao1,2, Yongfeng Zhang1, Bo Deng2

  • 1Department of Orthopedics, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi 710032, China.

Materials today. Bio
|June 12, 2025
PubMed
概括

这项研究开发了素功能化微球 (GM@mTG-V) 用于治疗椎间盘退化 (IVDD). GM@mTG-V 减少炎症和氧化应激,促进早期IVDD的组织再生.

关键词:
细胞外矩阵 (ECM) 是一个细胞外矩阵.炎症反应是一种炎症反应.椎间盘退化症 (IVDD) 是一种疾病.机械微环境 机械微环境瓦尼林是一种

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In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
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