使用全球结核病投资组合模型优化结核病政策:经济分析
medRxiv : the preprint server for health sciences
|June 12, 2025
概括
一个新的开源模型估计了不同人群的结核病 (TB) 护理成本,有助于为全球结核病目标分配资源. 该工具为投资案例提供信息,并优先考虑对最大影响力的干预措施.
科学领域:
- 全球卫生经济学全球卫生经济学
- 流行病学 流行病学
- 卫生系统研究 卫生系统研究
背景情况:
- 结核病 (TB) 是全球主要的卫生挑战,特别是在低收入和中等收入国家.
- 有效的资源配置对于实现世界卫生组织 (WHO) 消除结核病的目标至关重要.
- 现有的成本计算工具缺乏全面的全球结核病分析能力.
研究的目的:
- 开发一个新的,开源的结核病成本模型,用于详细的全球分析.
- 模拟跨不同人口群体和护理途径的结核病护理级联.
- 为结核病控制提供战略投资和资源配置的信息.
主要方法:
- 开发了一个模拟结核病查,诊断,治疗和预防级联的开源模型.
- 根据世卫组织指导方针 (患者和提供者发起的途径) 纳入20个不同的人口群体.
- 针对肺状况,年龄,艾滋病毒/ART状况,药物敏感性和大规模疫苗实施变化的建模成本.
主要成果:
- 该模型估计了实施2023-2030年结核病全球计划的成本,包括新的工具和护理标准.
- 在29个高负担国家的资金限制下,优化程序确定了最大结核病影响策略.
- 结果为全球基金第八次补充 (2027-2029) 的投资案例提供了信息.
结论:
- 新的结核病成本计算模型更好地反映了结核病护理的复杂性和多样性.
- 为全球结核病战略分析提供了更好的透明度,灵活性和政策相关性.
- 在投资案例中提供信息和优先考虑干预措施,以在资源限制下获得最大影响的价值.
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