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Updated: Jun 13, 2025

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
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In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

Published on: August 20, 2019

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多基因风险和罕见变体在异形性肺纤维化内型

Anna Duckworth, Leigh Jackson, Harry Green

    medRxiv : the preprint server for health sciences
    |June 12, 2025
    PubMed
    概括

    这项研究表明,常见和罕见的遗传变异都会导致异常性肺纤维化 (IPF) 风险. 端粒长度多基因风险评分 (TL-PRS) 提高了IPF预测,特别是在特定的遗传内型.

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