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综合性多omics方法识别分子途径并改善阿尔茨海默病风险预测

Rasika Venkatesh, Katie M Cardone, Yuki Bradford

    medRxiv : the preprint server for health sciences
    |June 12, 2025
    PubMed
    概括

    这项研究开发了先进的模型,通过整合遗传,基因表达和蛋白质数据来预测阿尔茨海默病 (AD) 风险. 这些综合性风险模型显著改善了AD风险预测的传统多基因评分.

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