相关实验视频
Updated: Jun 14, 2025

06:52
Reconstruct Human Retinoblastoma In Vitro
Published on: October 11, 2022
1.4K
从1980年到2023年的视网母细胞瘤研究趋势:一项长达44年的文献计量研究
Yun Zhao1, Yining Wang1, Yuchuan Wang1,2,3
1Department of Ophthalmology, Tianjin Eye Hospital, Tianjin, China.
Frontiers in oncology
|June 12, 2025
概括
这项研究分析了44年的视网膜母细胞瘤 (RB) 研究,揭示了美国和中国是领导者. 未来的热点包括液体活检和这种儿童眼癌的先进化疗技术.
科学领域:
- 眼科医生 眼科 眼科
- 儿科瘤学 儿科瘤学
- 图书统计学 图书统计学
背景情况:
- 视网母细胞瘤 (RB) 是儿童最常见的眼内恶性瘤,对视力和生命构成重大风险.
- 及时治疗对于控制这种侵袭性的儿童眼癌至关重要.
研究的目的:
- 从1980年到2023年,分析视网膜母细胞瘤 (RB) 的全球研究趋势.
- 为了比较不同国家,机构和作者在RB研究中的贡献.
- 确定视网膜母细胞瘤领域的新兴研究热点和未来方向.
主要方法:
- 从Web of Science数据库 (1980-2023) 中对4156个RB相关出版物的图书统计分析.
- 使用VOSviewer,R软件,Bibliometrix,Origin 2024和CiteSpace进行数据分析和可视化.
- 分类出版物按年份,国家/地区,机构,期刊,作者和关键词进行分类,以绘制研究格局.
主要成果:
- 在RB出版物显著增加,从1980年的13个到2023年的237个.
- 美国以1662个出版物 (39.99%) 领先,其次是中国 (539) 和印度 (377).
- 托马斯·杰斐逊大学是最多产的机构;主要期刊包括*调查性眼科和视觉科学*, *英国眼科杂志*和*眼科*.
结论:
- 美国,中国,印度,加拿大和德国是全球领先的RB研究.
- 著名的机构和研究人员继续推动视网膜母细胞瘤的进步.
- 液体活检,静脉内化疗和静脉内化疗代表着未来的研究前沿.
相关概念视频
The Retinoblastoma Gene
4.1K
Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
4.1K
Tumor Progression
6.3K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
6.3K

