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Updated: Jun 13, 2025

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基因修改重塑RNA折叠的景观和合成和天然RNA中的结构功能关系

Ewan McRae, Deepak Yadav, Haoyun Yang

    Research square
    |June 12, 2025
    PubMed
    概括

    像5-甲基氨酸和N1-甲基伪尿氨酸这样的修饰基对RNA3D结构产生影响,影响折叠和功能. 这些修改可以稳定非正典安排,影响治疗和合成RNA的设计.

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