艾滋病病毒感染黑人成年人的ART坚持的社会决定因素
Research square
|June 12, 2025
概括
健康的社会决定因素,如住房稳定性和健康素养,显著影响艾滋病毒感染黑人 (PWH) 的抗逆转录病毒治疗 (ART) 坚持. 针对这些因素的有针对性的干预措施对于改善治疗结果和健康公平至关重要.
科学领域:
- 公共卫生 公共卫生
- 健康差异 在健康上的差异
- 艾滋病毒/艾滋病研究研究
背景情况:
- 与其他种族/族群相比,美国艾滋病毒感染黑人 (PWH) 的抗逆转录病毒疗法 (ART) 坚持率较低.
- 健康的社会决定因素 (SDOH) 被认为是影响ART坚持的重要因素,有记录的差异不成比例地影响黑人社区.
- 该iC-CHANGE研究此前评估了短信干预措施对黑人PWH的ART坚持.
研究的目的:
- 检查健康的社会决定因素 (SDOH) 和艾滋病毒感染黑人 (PWH) 的纵向ART坚持措施之间的关系.
- 确定与ART遵守相关的特定SDOH因素,以告知有针对性的干预措施.
主要方法:
- 90名黑人PWH的队列接受了个性化的,文化适应的,自动化的短信干预.
- 用视觉模拟尺度,三项问卷和每天12周间隔的短信回复来测量ART的坚持.
- 使用线性和物流混合效应回归模型来分析SDOH和ART坚持之间的关联.
主要成果:
- 住房稳定性与所有测量方法 (p ≤ .02) 中更高的ART坚持有显著的关联.
- 年龄较大与视觉模拟尺度上更高的坚持相关 (p = .008),但通过每日短信的坚持较低 (p = .03).
- 改善的健康素养与通过短信响应测量的ART坚持有积极的关联 (p < .02).
结论:
- 针对住房稳定和健康素养的干预措施对于提高艾滋病毒感染黑人之间的ART坚持至关重要.
- 将SDOH考虑纳入临床护理途径可以改善治疗结果,促进PWH的健康公平.
- 解决社会经济因素对于在弱势群体中有效管理艾滋病毒至关重要.
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