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Updated: Jun 13, 2025

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
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Published on: March 15, 2024

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NOTCH3 驱动脂肪酸氧化和铁死抵抗在侵略性脑膜瘤

Nishanth S Sadagopan, Mateo Gomez, Shashwat Tripathi

    Research square
    |June 12, 2025
    PubMed
    概括

    NOTCH3信号驱动积极的脑膜瘤向脂肪酸氧化,耗尽脂质并赋予对铁亡的抵抗力. 这种代谢转变凸显了NOTCH3阳性瘤的潜在脆弱性.

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