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Updated: Jun 13, 2025

Isolation Protocol of Mouse Monocyte-derived Dendritic Cells and Their Subsequent In Vitro Activation with Tumor Immune Complexes
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Setdb2通过两种不同的表观遗传机制调节巨细胞的炎症触发诱导训练免疫力

Timothy Osborne, Anant Jaiswal, Laszlo Halasz

    Research square
    |June 12, 2025
    PubMed
    概括

    天生的免疫细胞通过表观遗传变化开发训练免疫力. 一种表观遗传修饰剂Setdb2在这个过程中起着关键作用,对病原性与无菌性触发物有不同的炎症和代谢途径产生影响.

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