对青少年的味觉和嗅觉功能的评估,与1型糖尿病的持续时间相关
Grzegorz Sobek1, Paweł Jagielski2, Mariusz Dąbrowski3
1Faculty of Health Sciences and Psychology, Collegium Medicum, University of Rzeszów, Rzeszów, Poland.
Pediatric diabetes
|June 12, 2025
概括
患有1型糖尿病 (T1D) 的青少年表现出甜味敏感度增加,如果诊断超过10年,嗅觉识别受损. 糖尿病的持续时间会影响年轻人的味觉和嗅觉.
科学领域:
- 内分泌学 在内分泌学.
- 神经学 神经学
- 感官科学 感官科学
背景情况:
- 嗅觉功能障碍是潜在的糖尿病神经病变症状,影响饮食坚持和血糖控制.
- 糖尿病的味道和气味的改变会影响患者的治疗和生活质量.
- 研究1型糖尿病 (T1D) 青少年的感官变化对于了解疾病影响至关重要.
研究的目的:
- 为了比较T1D青少年的味觉感知和嗅觉功能与对照组.
- 为了确定T1D的持续时间是否会影响感官变化.
- 评估T1D,味觉/嗅觉功能和潜在的神经病变指标之间的关系.
主要方法:
- 研究包括11-15岁的T1D青少年和来自波兰东南部的对照组.
- 使用味道条 (甜,,酸,苦) 和甲 (PROP) 纸来评估味觉感知.
- 使用12项U-Sniff测试评估的嗅觉功能.
主要成果:
- 与对照人群相比,患有T1D的青少年对甜味的敏感性明显更高 (p=0.0001).
- 两组之间嗅觉功能 (U-Sniff测试) 没有总体差异,但T1D患者患有超过10年的糖尿病 (p=0.0370) 的得分明显较低.
- 长期T1D青少年比健康的同龄人更经常错误地识别苦味.
结论:
- 糖尿病的持续时间是T1D青少年味觉和嗅觉变化的重要因素.
- 增加的甜味敏感性和受损的嗅觉识别可能与长期的T1D有关.
- 这些感官变化凸显了T1D的全身影响,并可能影响饮食选择和管理.
相关概念视频
Taste Buds and Receptors
1.9K
Gustation, or the sense of taste, is intrinsically linked to the anatomical structures located on the tongue. This organ's surface, along with the entirety of the oral cavity, is adorned with stratified squamous epithelium. Evident on the tongue are elevated structures known as papillae (singular = papilla), which house the mechanisms for the transduction of gustatory stimuli. Four distinct types of papillae exist, each identified by their unique morphological attributes: the circumvallate,...
1.9K
Diabetes Mellitus: Overview and Type I Subtype
2.5K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
2.5K
Diabetes: Symptoms, Diagnosis, and Complications
520
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
520
Diabetes Mellitus: Type 2 and Gestational
2.3K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.3K


