最佳骨肌肉质量指数和发生的心血管事件:从纵向分析的见解
Tingting Hu1, Yiting Xu1, Xiaoya Li1
1Department of Endocrinology and Metabolism, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine; Shanghai Clinical Center for Diabetes; Shanghai Diabetes Institute; Shanghai Key Laboratory of Diabetes Mellitus, Shanghai 200233, China.
European journal of cardiovascular nursing
|June 12, 2025
概括
骨肌肉质量 (SMM) 指数预测了老年人的心血管事件. 以体重指数 (SMM/BMI) 调整后的SMM显示出对心血管事件的最强的预测能力.
科学领域:
- 老年学是指老年学的学科.
- 心脏病学 心脏病学
- 营养科学 营养科学
背景情况:
- 骨肌肉质量 (SMM) 对于代谢健康至关重要.
- 之前的研究已经探索了各种SMM指数来预测健康结果.
- 不同的SMM调整对老年人群中心血管事件的预测价值仍然不清楚.
研究的目的:
- 评估和比较SMM指数对中年和老年人心血管事件的预测性能.
- 评估SMM指数与不同身体形状子组内心血管事件的相关性.
主要方法:
- 一组1374名个人 (年龄在50-80岁) 被跟踪平均7.5年.
- 骨肌肉质量 (SMM) 用生物电阻分析测量,并根据体重 (SMM/Wt),体重指数 (SMM/BMI) 和内脏脂肪面积 (SMM/VFA) 进行调整.
- 心血管事件被记录和验证,通过统计分析,包括危险比率和重新分类改进.
主要成果:
- 最低的SMM/Wt,SMM/BMI和SMM/VFA三位数与心血管事件风险增加有关 (HRs分别为1.80,1.83和1.56).
- 与SMM/Wt和SMM/VFA相比,SMM/BMI表现出更好的预测性能,由改进的C统计和重新分类指标表明.
- SMM/BMI与心血管事件之间的关联在各种人口统计和身体形状子组中是一致的.
结论:
- 在中年和老年人中,SMM指数与心血管事件发生率有显著的关联.
- 根据体重指数 (SMM/BMI) 调整的SMM成为心血管事件的强有力的肌肉相关风险因素.
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