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Updated: Jun 15, 2025

Isolation of Fidelity Variants of RNA Viruses and Characterization of Virus Mutation Frequency
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Published on: June 16, 2011

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SARS-CoV-2 的突变率在不同部位之间非常可变,并受到序列上下文,基因组区域和RNA结构的影响

Hugh K Haddox1, Georg Angehrn2, Luca Sesta2,3

  • 1Computational Biology Program, Fred Hutchinson Cancer Research Center, Seattle, WA 98102, United States.

Nucleic acids research
|June 12, 2025
PubMed
概括

SARS-CoV-2 (严重急性呼吸系统综合征冠状病毒2) 呈现出高突变率,具有显著的特定部位变异性. 这种变异性受到序列上下文和RNA结构的影响,揭示了对病毒进化的洞察力.

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