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Updated: Jun 13, 2025

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一个超标离散扩散3DRNA反向折叠模型用于功能性RNA设计

Dongyue Hou1, Shuai Zhang2, Mengyao Ma2,3

  • 1School of Pharmaceutical Sciences, Shanghai Engineering Research Center of Immunotherapeutics, Fudan University, Shanghai 201203, China.

Journal of chemical information and modeling
|June 12, 2025
PubMed
概括

一个新型的生成模型RIdiffusion使用过度波形几何学来设计功能性RNA3D结构. 这种方法克服了数据的局限性,为生物技术和生物医学应用实现了高效的RNA反折叠.

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