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Updated: Jun 13, 2025

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核体的融合进化促进了SARS-CoV-2适应人类感染的过程

Kumari G Lokugamage1, Yiyang Zhou1,2, R Elias Alvarado1

  • 1Department of Microbiology and Immunology, The University of Texas Medical Branch, Galveston, Texas, USA.

Journal of virology
|June 12, 2025
PubMed
概括

三种SARS-CoV-2核蛋白突变 (R203K + G204R,R203M,T205I) 增强了人类细胞感染和病毒适应性. 这些突变显示出明显的酸化模式,并在蝙蝠细胞中减少复制,表明适应人类传播.

关键词:
在 COVID-19 疫情中,这就是SARS-CoV-2病毒.它是核体的核体.有关关注的变种.

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