[异位性血指数及其与绝经后妇女心血管风险的关联:基于人口的研究]
Marcela Sepúlveda González1, Samuel Durán Aguero2, Lincoyán Fernández-Huerta3
1Centro de Salud Familiar N°1, Dirección de Atención Primaria, Servicio de Salud Metropolitano Central, Santiago, Chile.
血动脉原指数有效评估绝经后智利妇女的心血管风险. 晚期更年期显示较高的静缩血压和显著差异的动脉动脉指数.
科学领域:
- 心血管健康 心血管健康
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 更年期是一个关键的衰老阶段,与血管功能障碍和心血管风险因素有关.
- 更年期期间的荷尔蒙变化反映了老年男性的心血管问题.
研究的目的:
- 根据更年期的阶段调查智利妇女的血动脉生成指数和心血管风险之间的关联.
- 评估动脉质指数在评估不同绝经阶段心血管风险方面的有用性.
主要方法:
- 2016-2017年国家健康调查数据的二次分析.
- 包括742名年龄在40-70岁的女性,按早期或晚期更年期分类,使用STRAW分阶段系统.
- 脂质概况和动脉动脉产物指数的计算,与统计分析,包括t测试,曼-惠特尼和千平方测试.
主要成果:
- 观察到营养不良 (74.4%) 和腹部肥胖 (88%) 的高患病率,平均BMI为30kg/m2.
- 在更年期晚期的女性中,静脉血压显著更高 (8 分).
- 在更年期阶段之间发现了动原体指数的显著差异,而血动原体指数显示了与心血管风险的最强相关性.
结论:
- 血动脉质指数和动脉质系数是对绝经后妇女心血管风险评估的具有成本效益的生物标志物.
- 这些指数为这一人口群体中心血管风险分层提供了宝贵的见解.
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