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全球患病率,复发率和与自发性CSF风相关的风险因素-A元分析

Srivatsa Surya Vasudevan¹, Victor Albornoz¹, Sydney Schwab²

¹Department of Otolaryngology-Head and Neck Surgery, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

|June 12, 2025

概括

自发性脑脊液 (CSF) 耳病影响37.8%的患者,肥胖和高血压是常见的危险因素. 手术后的复发率约为10.3%.

科学领域:

神经外科神经外科
耳鼻喉科耳鼻喉科耳鼻喉科
流行病学流行病学

背景情况:

自发性脑脊液 (CSF) 耳是一种从鼻子或耳朵中 CSF 泄漏的特征.
了解其流行,复发和相关风险因素对于有效管理至关重要.

研究的目的:

为了确定自发的CSF otorrhea的流行率和术后复发率.
为了确定与自发的CSF耳相关的流行风险因素.

主要方法:

在PubMed,Embase,Web of Science和ScienceDirect进行了系统的文献搜索.
采用随机效应模型的元分析,从24项涉及1059名患者的研究中汇集了数据.

主要成果:

自发性CSF耳的总体患病率估计为37.8%.
常见的危险因素包括肥胖 (73.9%),高血压 (63.4%),空腹 (49.3%) 和阻塞性睡眠呼吸暂停 (37.6%).
手术后复发率为10.3%,OSA和先前脑膜炎与男性性别负面相关.

结论:

这一元分析提供了第一个全面的估计自发的CSF耳发病率和术后复发.
肥胖,高血压,空和OSA是显著的风险因素,与女性性别有着显著的关联.

关键词:

异常性中枢神经液耳垂症 (CSF otorrhea).这是一个自发的CSF泄漏.自发的脑脊液耳鼻.tegmen dehiscence CSF泄露的原因之一是因为在骨中,有CSF泄漏.

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