PRKACAL205R

Anagha Kalle1, Jian Wu2, Caesar Tawfeeq3

  • 1Advanced Academic Program, Johns Hopkins University, Washington, DC 20001.

概括

在PRKACA基因中的L205R突变破坏了蛋白激酶A (PKA-C) 功能,改变了基质特异性和全网络. 这项研究揭示了这种常见的库辛综合征突变如何影响PKA-C动态和合作性.

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