Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Fractures: Bone Repair01:27

Fractures: Bone Repair

3.1K
Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
3.1K
Bone Disorders01:29

Bone Disorders

3.4K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.4K
Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

3.2K
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
3.2K
Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

2.9K
Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
2.9K
Essential Minerals for Bone Health01:31

Essential Minerals for Bone Health

3.8K
The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
3.8K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

OMA1 protects from liver injury and tumorigenesis during aging by controlling hepatic immunogenicity.

The EMBO journal·2026
Same author

A decline in skeletal muscle NOX4 abrogates exercise-induced adaptive homeostasis and exacerbates biological aging.

Science advances·2026
Same author

Gender Differences in Circulating TFAM Levels Are Associated with Functional Impairment and Sarcopenia.

Biomedicines·2026
Same author

Human whole-blood NAD<sup>+</sup> levels do not vary with age or lifestyle interventions.

Nature metabolism·2026
Same author

Estradiol loss, the "estrobolome," and midlife symptoms: what the gut microbiome adds to menopause care.

Menopause (New York, N.Y.)·2026
Same author

The antimetastatic effects of calorie restriction are negated by voluntary exercise in an aggressive breast cancer mouse model.

Proceedings of the National Academy of Sciences of the United States of America·2026

相关实验视频

Updated: Jun 16, 2025

Author Spotlight: Enhancing Accuracy and Reproducibility in Whole Bone Bending Tests
04:20

Author Spotlight: Enhancing Accuracy and Reproducibility in Whole Bone Bending Tests

Published on: September 1, 2023

770

预防脆弱性骨折的建议:国际专家和伊伯罗美洲科学会的共识.

Pilar Sáez-López1,2, César Aldecoa Álvarez-Santullano3, Rosa Arboiro-Pinel4

  • 1Hospital La Paz Research Institute (IdiPAZ), Madrid, Spain.

Archives of osteoporosis
|June 12, 2025
PubMed
概括
此摘要是机器生成的。

这一共识提供了十个关键建议,以预防脆弱性骨折和改善患者护理. 它强调跨卫生保健部门的多学科合作,以获得更好的结果.

关键词:
达成共识声明 达成共识声明脆弱性骨折是一种脆弱性骨折.骨质疏松症是一种骨质疏松症.利益相关者 利益相关者

更多相关视频

Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population
09:02

Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population

Published on: January 31, 2025

425
Establishing a Diaphyseal Femur Fracture Model in Mice
05:46

Establishing a Diaphyseal Femur Fracture Model in Mice

Published on: December 9, 2022

2.0K

相关实验视频

Last Updated: Jun 16, 2025

Author Spotlight: Enhancing Accuracy and Reproducibility in Whole Bone Bending Tests
04:20

Author Spotlight: Enhancing Accuracy and Reproducibility in Whole Bone Bending Tests

Published on: September 1, 2023

770
Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population
09:02

Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population

Published on: January 31, 2025

425
Establishing a Diaphyseal Femur Fracture Model in Mice
05:46

Establishing a Diaphyseal Femur Fracture Model in Mice

Published on: December 9, 2022

2.0K

科学领域:

  • 老年学是一门学科.
  • 整形外科 整形外科 整形外科
  • 公共卫生 公共卫生

背景情况:

  • 脆弱性骨折是一个显著且日益严重的公共卫生问题.
  • 与这些骨折相关的发病率,残疾和医疗保健支出不断增加,需要采取紧急行动.

研究的目的:

  • 建立一个多学科的共识,防止脆弱性骨折.
  • 通过协调医疗保健努力,概述改善患者护理的关键建议.

主要方法:

  • 由西班牙国家部骨折登记处 (RNFC) 协调的国际专家小组召开了会议.
  • 一个名义上的小组技术涉及300多名专业人士和31个社会被用来制定十个核心建议.
  • 该共识经历了多次审查,并于2024年3月最终确定.

主要成果:

  • 制定了十项可行的建议,涵盖卫生政策,脆弱性和跌倒管理,临床指南,注册表,专业单位 (骨架病房,骨折联络服务 - FLS),"脆弱性骨折代码",初级保健赋权,患者参与,公众意识和研究促进.
  • 具体建议包括将骨质疏松症和骨折护理纳入卫生政策,并促进患者报告结果的研究.

结论:

  • 脆弱性骨折是一个重大的公共卫生挑战,需要统一的,基于证据的指导.
  • 共识为决策者,医疗保健专业人员和患者组织提供了一个框架.
  • 实施旨在通过协调,多学科的护理来减少骨折的发生率和改善患者的治疗结果.