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Updated: Jun 13, 2025

Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology
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Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology

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在阿尔茨海默病病理学和认知能力方面,海马体对氧化合成的选择性脆弱性

Alberto Fernando Oliveira Justo1,2,3, Eliana Cristina de Brito Toscano4, Natalia Gomes Goncalves5

  • 1Division of Geriatrics, Department of Internal Medicine, University of São Paulo Medical School, São Paulo, Brazil. albertofojusto@gmail.com.

Neurochemical research
|June 12, 2025
PubMed
概括

这项研究发现,神经和诱导性氧化合成酶 (NOS) 在阿尔茨海默氏症 (AD) 海马中过度表达,与AD病理和认知衰退相关. 内皮NOS和3-甲氨酸显示出有限的关联.

关键词:
3 - 尼铁氨酸 (3-NT) 的使用.阿尔茨海默病的疾病阿尔茨海默病的疾病.认知 认知是一种认知.河马子区域的子区域我们的NOS NOS神经质斑块是一种神经质斑块.神经纤维状的纠.神经炎症是一种神经炎症.氧化合成酶是一种氧化合成酶.氧化应激是一种氧化应激.

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