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Updated: Jun 13, 2025

HLA-Ig Based Artificial Antigen Presenting Cells for Efficient ex vivo Expansion of Human CTL
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抗原特异性CD4+ T辅助细胞的选择性扩张和分化由工程外细胞囊泡进行

Ryouken Kimura1,2, Tomoyoshi Yamano1,3, Uryo Onishi1

  • 1Department of Immunology, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan.

Drug delivery
|June 12, 2025
PubMed
概括

工程抗原呈现细胞外囊泡 (AP-EVs) 有效地扩大和分化T细胞. AP-EVs-Th1在黑色素瘤模型中表现出显著的抗瘤作用,突出了它们在癌症免疫治疗中的潜力.

关键词:
CD4+ T 细胞是 CD4+ T 细胞.细胞外囊泡 细胞外囊泡癌症免疫疗法免疫疗法选择性扩张选择性扩张有针对性的细胞因子输送.

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