在系统性红血性狼的女性中,VO2对动力学和有氧运动训练
Zoe Morris1,2, Nathan Camarillo1, Sarfaraz Hasni3
1Rehabilitation Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD, USA.
有氧运动训练改善了全身性红斑狼 (SLE) 妇女的氧气吸收 (VO2) 动力学. 这种VO2动力学上的增强与更好的心肺呼吸能力相关,表明血液循环功能得到改善.
科学领域:
- 运动生理学 运动生理学
- 类风湿病学 类风湿病学
背景情况:
- 疲劳是患有系统性红斑狼 (SLE) 的女性的主要症状.
- 与健康个体相比,患有SLE的女性在运动上表现出较慢的氧气吸收 (VO2).
- 有氧运动训练对SLE的VO2动力学的影响尚未得到充分证实.
研究的目的:
- 在SLE的女性中描述VO2的动力学.
- 评估12周有氧运动训练 (AET) 对该人群的VO2动力学的影响.
主要方法:
- 16名患有SLE的女性接受了心肺运动测试和持续工作率测试,在经过12周的监督强力跑步机AET之前和之后进行了测试.
- 测量包括肺气交换,心率 (HR) 和肌肉脱氧 ([HHb]).
- 分析了VO2,HR和[HHb]上的动力学,以及子集中的[HHb]/VO2比率.
主要成果:
- AET显著加快了VO2上的动力学 (p < .001).
- 更快的VO2上运动与改善的峰值VO2 (rs = -0.562,p = .024) 和峰值工作率 (rs = -0.535,p = .033) 相相关.
- 心率动力学也有所改善 (p = .022),但肌肉脱氧化动力学没有显著变化 (p = .508).
结论:
- 监督的有氧运动训练可以提高SLE女性的VO2上运动.
- 改善的VO2动力学与心肺呼吸能力的提高有关.
- 同时加速HR的动力学表明,SLE患者在AET之后的中央循环适应.
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