使用国际原子能机构的TRS-398协议及其修订版进行基准剂量测量的量化和比较
Mohammad Abdul Fatha1, Sathiya Raj2, Y S Pawar3
1RadiationPhysics, Kidwai Memorial Institute of Oncology, Bangalore, India. abdulfatha4698@gmail.com.
Radiological physics and technology
|June 12, 2025
概括
这项研究比较了国际原子能机构.
科学领域:
- 医学物理 医学物理
- 放射治疗剂量计 放射治疗剂量计
背景情况:
- 国际原子能机构 (IAEA) 制定了技术报告系列 (TRS-398) 用于在外部放射治疗中测量吸收剂量.
- TRS-398提供了一种标准化的方法,用于使用可追溯到计量研究所的校准离子化室来确定对水的吸收剂量.
- 精确的剂量测量对于有效和安全的放射治疗治疗至关重要.
研究的目的:
- 为了比较TRS-398原始协议及其修订版本之间的参考剂量测量,特别是10厘米深处的剂量 (D10).
- 评估使用不同的电离室和束类型对剂量测量比较的影响.
- 评估吸收剂量转换因子 (kQ,QO) 对测量精度的影响.
主要方法:
- 对平面化 (FF) 和平面化无波器 (FFF) 光子束 (6,10,15 MV) 进行了参考剂量测量,使用TRS-398及其修订版.
- 使用了两个具有可追溯校准系数的IBA电离室 (0.65 cm3 FC65-G和0.13 cm3 CC13).
- 吸收剂量到水 (Dw) 标准用于校准.
主要成果:
- 协议之间D10的差异在FC65-G室中为0.03%至0.63%,在CC13室中为-0.40%至-0.77%.
- 与旧的TRS-398.8.3相比,修订后的协议显示了高达0.63% (FC65-G) 和-0.77% (CC13) 的变化.
- 使用旧的kQ,QO值导致平均高估值为0.5%,低估值高达-0.77%,取决于室和梁类型.
结论:
- 修订后的TRS-398协议影响了参考剂量测量,根据电离室和光束特性观察到的变化.
- 选择kQ,QO值显著影响剂量计的准确性,可能导致过高或低估吸收剂量.
- 建议遵守修订后的协议,以获得准确和一致的放射治疗剂量计.
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