相关实验视频

Updated: May 5, 2026

Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers
08:28

Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers

Published on: September 19, 2017

7.9K

光激活分子准G-四重复核酸

Marta Dudek1, Clément Cabanetos2, Marco Deiana3

  • 1Wroclaw University of Science and Technology: Politechnika Wroclawska, Faculty of Chemistry, Wroclaw, POLAND.

Chemistry (Weinheim an der Bergstrasse, Germany)
|June 12, 2025
PubMed
概括

响应光的分子为癌症治疗提供了对G-四复合体 (G4s) 的精确控制. 这种光药理学方法使得癌细胞中的向DNA损伤成为可能,进步了精确瘤学.

关键词:
在G-quadruplex中使用.照相中的配体.摄影药理学 摄影药理学光敏化剂的光敏化剂.照片交换机 照片交换机

更多相关视频

Aptamer-Based Target Detection Facilitated by a 3-Stage G-Quadruplex Isothermal Exponential Amplification Reaction03:38

Aptamer-Based Target Detection Facilitated by a 3-Stage G-Quadruplex Isothermal Exponential Amplification Reaction

Published on: October 6, 2022

1.4K
Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes05:37

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes

Published on: April 4, 2025

384

相关概念视频

Inhibitors of Bacterial DNA Synthesis01:28

Inhibitors of Bacterial DNA Synthesis

Bacterial pathogens depend on precise and efficient DNA replication to sustain infection. Two type II topoisomerases—DNA gyrase and topoisomerase IV—are critical to this process, as they resolve DNA supercoiling and unlink chromosomes during replication. Fluoroquinolones, synthetic derivatives of quinolones, exploit this mechanism by stabilizing the transient DNA–enzyme cleavage complex, preventing strand religation, and causing lethal double-strand breaks. These...
130