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Updated: Jun 15, 2025

In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells
10:26

In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells

Published on: January 20, 2019

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突变EZH2改变了表观遗传网络,增加了B细胞淋巴瘤的表观遗传异质性

Ofir Griess1, Noa Furth1, Nofar Harpaz1

  • 1The Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel.

PLoS biology
|June 12, 2025
PubMed
概括

变异性增强体同源2 (EZH2) 显著影响淋巴瘤表观基因组,增加细胞异质性,并揭示新的致癌机制. 这项研究探讨了淋巴瘤中的表观遗传网络变化.

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