正念和太极拳治疗癌症健康 (MATCH) 研究:基于偏好的多站点随机比较有效性试验的主要结果
Linda E Carlson1, Jennifer M Jones2, Devesh Oberoi1
1Department of Oncology, University of Calgary, Calgary, AB, Canada.
概括
基于正念的癌症恢复 (MBCR) 和太极拳/千功 (TCQ) 都有效地减少了癌症幸存者的痛苦. 在这项比较试验中,患者偏好或随机分配没有影响情绪改善结果.
科学领域:
- 心理社会瘤学
- 心灵与身体的医学
- 相对有效性研究研究比较
背景情况:
- 癌症幸存者经常经历严重的痛苦和心理社会症状.
- 诸如基于正念的癌症恢复 (MBCR) 和太极拳/智功 (TCQ) 这样的心身干预措施显示出管理这些问题的前景.
- 在患癌症幸存者中缺乏MBCR和TCQ的直接比较研究.
研究的目的:
- 为了比较MBCR和TCQ在减少癌症幸存者的痛苦方面的有效性.
- 评估患者偏好与随机分配对干预结果的影响.
- 作为主要结局,评估总情绪障碍 (TMD) 的改善.
主要方法:
- 进行了一项实用性的多站点随机比较有效性试验.
- 参与者可以选择他们喜欢的干预措施 (MBCR或TCQ) 或随机分配.
- 2: 1随机化将参与者分配到即时干预或等候名单对照组.
主要成果:
- 587名癌症幸存者 (75%为女性,平均年龄为60.7岁) 参加了这项研究,其中乳腺癌最为普遍.
- 与等候名单对照组相比,MBCR和TCQ组在TMD中均显示出显著的改善.
- 特定的情绪子表格在MBCR (压力,愤怒,活力) 和TCQ (愤怒,抑郁,活力) 中得到了更大的改善.
结论:
- 无论是MBCR还是TCQ都有效地改善了痛苦的癌症幸存者的情绪.
- 患者在干预选择中的选择并没有改变积极的结果.
- 这项研究强调了在幸存者护理中心身干预的价值.
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