典型的纤维性过敏性肺炎模式在胸部计算机断层扫描的结果
Christopher J Ryerson1, Daniel-Costin Marinescu2, Nestor L Muller3
1University of British Columbia, Medicine, Vancouver, British Columbia, Canada; chris.ryerson@hli.ubc.ca.
概括
患有典型纤维性过敏性肺炎 (fHP) 成像模式的患者通常会接受其他诊断,包括结缔组织疾病相关的间歇性肺病 (CTD-ILD). 没有确定的暴露的人面临更糟糕的结果,并且可能在以后发展出CTD特征.
科学领域:
- 肺部医学 肺部医学
- 放射学 放射学是一门学科.
- 类风湿病学 类风湿病学
背景情况:
- 指南定义了纤维性过敏性肺炎 (fHP) 的典型成像模式.
- 在这种模式中,各种多学科诊断的频率和特征尚未得到充分理解.
研究的目的:
- 在典型的fHP成像模式中调查不同多学科诊断的频率,临床特征和结果.
- 为了在这些诊断中比较患者的特征和疾病行为.
主要方法:
- 在胸部CT上具有典型的fHP模式的患者从一个潜在的注册表中被识别出来.
- 通过共识建立了多学科诊断,将患者分为fHP暴露,fHP无暴露和CTD-ILD.
- 在诊断组中比较了临床,放射性特征和结果.
主要成果:
- 在164名患者中,30%有暴露的fHP,34%没有暴露的fHP,22%有CTD-ILD.
- 临床和CT特征在各个诊断中各不相同.
- 没有确定的暴露的fHP患者表现出更糟糕的肺功能下降和存活率,14%的患者在随访期间发展出CTD特征.
结论:
- 在CT上典型的fHP成像模式通常表明非HP诊断,如CTD-ILD.
- 疾病特征和行为在典型的fHP模式中的多学科诊断之间存在显著差异.
- 没有确定的HP暴露的患者有更高的CTD发展风险.
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