速度和吸烟杀死:一个时间变化的生存分析,将甲基胺使用,吸烟和性少数群体男性的死亡率联系起来
Grace Yi1, Marjan Javanbakht2, Allison D Rosen3
1David Geffen School of Medicine at UCLA, 10833 Le Conte Ave, Los Angeles, CA 90095, United States.
The International journal on drug policy
|June 12, 2025
概括
持续使用甲基胺和每天吸烟超过半包香烟显著增加性少数群体男性的死亡风险. 这些发现凸显了改善健康结果的有针对性的干预措施的必要性.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 药物使用研究研究 药物使用研究
背景情况:
- 性少数群体男性 (SMM) 面临高比例的甲基胺使用和艾滋病毒.
- 以前的研究集中在寻求治疗的人群上,限制了概括性.
- 本研究研究了基于社区的SMM队列中的物质使用和死亡率.
研究的目的:
- 调查甲基胺使用,吸烟和死亡风险之间的关联,在基于社区的SMM队列中.
- 评估物质使用的动态模式如何随着时间的推移影响死亡率.
- 为SMM提供公共卫生干预信息.
主要方法:
- 在洛杉矶对541名SMM进行了纵向队列研究 (2014-2023).
- 通过调查和临床评估,每两年收集物质使用和健康数据.
- 考克斯比例危险回归与时间变化的共变量来分析死亡风险.
主要成果:
- 每日使用甲基胺与4.45倍的死亡风险增加有关.
- 每周使用甲基胺的死亡风险增加了3.32倍.
- 吸烟>1⁄2包/天独立增加了3.28倍的死亡风险.
结论:
- 持续使用甲基胺和大量吸烟增加了SMM的死亡风险.
- 针对行为疗法和风险查的干预措施至关重要.
- 缓解早期死亡率和改善SMM的健康结果是优先事项.
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