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Updated: Jun 14, 2025

Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies
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Published on: September 30, 2016

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LncRNA USP2-AS1通过PHLDA2/PI3K/AKT轴促进结肠直肠癌的发展

Jing Zhu1, Shuhui Lin1, Lisha Chang1

  • 1Department of Oncology, the Second Affiliated Hospital of Nanjing Medical University, 121 Jiangjiayuan Road, Nanjing, China.

Experimental cell research
|June 12, 2025
PubMed
概括

长非编码RNAUSP2-AS1在结直肠癌 (CRC) 中过度表达,促进瘤生长和进展. USP2-AS1通过IGF2BP2和miR-134-5p准PHLDA2,激活PI3K/AKT通路,使其成为CRC的潜在治疗点.

关键词:
在IGF2BP2BP2的基础上.在PHLDA2中使用.在PI3K/AKT中使用.在USP2-AS1中使用.结肠直肠癌是什么意思

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