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Updated: Jun 14, 2025

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
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对立的谱系特异因子在肺腺癌中诱导了前瘤杂交身份状态

Gabriela Fort1,2, Henry Arnold1,2, Soledad A Camolotto1

  • 1Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112, USA.

Genes & development
|June 12, 2025
PubMed
概括

肝细胞核因子4-α (HNF4α) 通过诱导混合细胞身份来驱动肺腺癌 (LUAD) 的进展. 准HNF4α或RAS/MEK信号可能会改善LUAD治疗结果.

关键词:
抑制了KRAS的抑制作用.混合身份 混合身份 混合身份血统的可塑性 血统的可塑性谱系指标 谱系指标肺部腺癌的癌症.

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