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儿童肝硬度的参考值使用剪切波弹性学.

Célia Charlier1, Saskia Vande Perre1, Béatrice Dubern2

  • 1Department of Radiology, Trousseau Hospital, APHP, Sorbonne Université, Paris, France.

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概括

本研究使用超声波剪切波弹性学 (SWE) 确定了健康儿童的肝脏弹性参考值. 值随着年龄的增长而下降,并因超声波探针而异,提供必要的临床数据.

关键词:
年龄年龄年龄年龄年龄年龄孩子 孩子 孩子 孩子肝脏硬 肝脏硬 肝脏硬剪切波弹性图形学 剪切波弹性图形学转换器 转换器 转换器超声波超声波是指超声波的使用.

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科学领域:

  • 儿科胃肠病学和肝病学
  • 医学成像和诊断 医学成像和诊断
  • 评估非侵入性肝病的评估.

背景情况:

  • 超声切割波弹性图 (SWE) 是一种非侵入性方法,用于评估慢性肝病中肝硬度.
  • 确定健康儿童肝脏弹性的特定年龄参考值对于临床实践至关重要.

研究的目的:

  • 用2D SWE,按年龄分层来确定儿科群体中肝弹性的参考值.
  • 为儿童和青少年提供基于年龄的肝脏弹性的规范性数据.

主要方法:

  • 对266名健康儿童 (0-19岁) 进行腹部超声波的回顾性分析.
  • 使用凸 (6C1) 和线性 (SL15-4) 传感器在佳能Aplio 500系统上测量肝脏弹性和剪切波速.
  • 将参与者分为五个年龄组进行分层,以分析年龄依赖的变化.

主要成果:

  • 整体肝脏弹性的中位数为5.50kPa (IQR 4.9-6.3).
  • 随着年龄的增长,肝脏的弹性和速度显著下降 (p < 10−3).
  • 凸起式 (5.20 kPa) 和线性 (6.2 kPa) 传感器之间的弹性值不同 (p < 10−4).

结论:

  • 这项研究提供了2D SWE.使用的健康儿童肝脏弹性的关键年龄分层参考值.
  • 这些发现突显了超声波探针对测量肝脏弹性值的影响.
  • 这些参考范围有助于准确解释儿科患者肝硬度测量结果.