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Updated: Jun 14, 2025

Imaging the Intracellular Trafficking of APP with Photoactivatable GFP
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Imaging the Intracellular Trafficking of APP with Photoactivatable GFP

Published on: October 17, 2015

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突触囊糖蛋白2A 减缓了粉样蛋白前体蛋白的粉样蛋白生成过程 通过 调节其细胞内贩运

Qian Zhang1, Xiao Ling Wang2, Yu Li Hou1

  • 1Department of Clinical Laboratory, Xuanwu Hospital, National Clinical Research Center for Geriatric Diseases, Capital Medical University, Beijing 100053, China.

Biomedical and environmental sciences : BES
|June 12, 2025
PubMed
概括

突触囊糖蛋白2A (SV2A) 影响粉样前体蛋白 (APP) 的分布,通过Arl5b通路促进其运输. 这一过程减缓了APP粉样蛋白降解,影响了粉样蛋白病理.

关键词:
阿尔茨海默氏症是阿尔茨海默氏症的一种疾病.粉样蛋白降解的降解粉样蛋白前体蛋白是一种前体蛋白.这是内分泌体系统.突触囊泡糖蛋白 2A 是一种突触囊泡糖蛋白.

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