一个瞬间语音合成神经假体
Maitreyee Wairagkar1, Nicholas S Card2, Tyler Singer-Clark2,3
1Department of Neurological Surgery, University of California, Davis, Davis, CA, USA. mwairagkar@ucdavis.edu.
Nature
|June 12, 2025
概括
这项研究提出了一种新的脑声神经假体, 这种脑电脑接口 (BCI) 恢复了患者的表达性沟通,
科学领域:
- 神经科学
- 生物医学工程
- 语音合成
背景情况:
- 脑电脑接口 (BCI) 在神经疾病中提供了恢复通信的潜力.
- 现有的BCI主要将神经活动转化为文字,
- 恢复自然,有表达力的声音对于有效的沟通至关重要.
研究的目的:
- 开发和演示用于合成可理解和表达的语音的神经假体.
- 解码神经活动以实时语音合成与闭环音频反.
- 让严重发言障碍的人使用自己的合成语音进行交流.
主要方法:
- 在患有肌缩侧面硬化症 (ALS) 的参与者中植入256个微电极.
- 开发了一个神经解码器, 将皮质内活动转化为语音信号,
- 启用实时语音合成与闭环音频反,允许调制歌曲和旋律.
主要成果:
- 从神经活动中精确合成参与者的声音, 包括语音内容.
- 成功解码和合成语言特征, 实现实时调制语调.
- 参与者可以用BCI合成的声音唱歌.
结论:
- 证明了脑对声音神经假体在患者中恢复表达能力的可行性.
- 这项技术有潜力显著提高严重脱节症患者的沟通能力和生活质量.
- 进一步的研究可以推进BCI技术,
相关概念视频
Nonconscious Mimicry
3.6K
Nonconscious mimicry occurs when individuals alter their mannerisms to match the behaviors and expressions of those nearby, without intention.
3.6K
Perception of Sound Waves
4.7K
The human ear is not equally sensitive to all frequencies in the audible range. It may perceive sound waves with the same pressure but different frequencies as having different loudness. Moreover, the perception of sound waves depends on the health of an individual's ears, which decays with age. The health of one's ears may also be affected by regular exposure to loud noises.
The pitch of a sound depends on the frequency and the pressure amplitude of the source. Two sounds of the same...
The pitch of a sound depends on the frequency and the pressure amplitude of the source. Two sounds of the same...
4.7K
Brain Waves
4.2K
Brain waves are electrical signals generated by the neurons in the brain, which are regularly monitored to measure mental activities. Brain waves and their frequency ranges can be measured using an electroencephalogram or EEG. There are four main types of brain waves, each with distinct characteristics:
4.2K
Higher Mental Functions of the Brain: Language
6.0K
Language is a system of communication that allows the expression of thoughts, ideas, and feelings. The brain processes language in both hemispheres.
Language formation and comprehension take place in the dominant hemisphere. The dominant hemisphere is responsible for understanding the meaning of spoken, written, or sign language, as well as the ability to communicate. For most people, the left hemisphere is the dominant one. The right hemisphere, then, gives tone and emotional context to the...
Language formation and comprehension take place in the dominant hemisphere. The dominant hemisphere is responsible for understanding the meaning of spoken, written, or sign language, as well as the ability to communicate. For most people, the left hemisphere is the dominant one. The right hemisphere, then, gives tone and emotional context to the...
6.0K
Neurons as Communicators of the Brain
5.2K
Neurons, the fundamental units of the brain and nervous system, function as the primary transmitters of information throughout the body. Their ability to communicate through electrical and chemical signals is vital for every bodily function, from regulating the heartbeat to processing complex thoughts. Each neuron has three main components: the cell body (soma), dendrites, and an axon, each specialized to facilitate swift and efficient neural communication.
Cell Body
The cell body, also known...
Cell Body
The cell body, also known...
5.2K
Sleepwalking and Sleep Talking
1.8K
Somnambulism, commonly known as sleepwalking, involves individuals engaging in activities ranging from simple walking to more complex behaviors such as driving. Sleepwalking typically occurs during the slow-wave sleep stages 3 and 4 early in the night when the person is not dreaming, contradicting the myth that sleepwalkers are acting out their dreams.
Factors that increase the likelihood of sleepwalking include sleep deprivation and alcohol consumption. Contrary to common beliefs, it is safe...
Factors that increase the likelihood of sleepwalking include sleep deprivation and alcohol consumption. Contrary to common beliefs, it is safe...
1.8K


