基于红外热学和人工智能的可穿戴设备用于下淋巴结查乳腺癌
Xiaoying Zhong1,2, Jinqiu Deng3, Ping Lu1
1Department of Breast Surgery, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, No. 3 Dongdan, Dongcheng District, Beijing, China.
Breast cancer research : BCR
|June 12, 2025
概括
一个基于人工智能的红外热像系统 (AI-IRT) 显示了在乳腺癌患者中检测带淋巴结转移的前景. 这种AI-IRT系统在内部和外部验证队伍中实现了高精度,改善了诊断可访问性.
科学领域:
- 医疗成像医学成像
- 人工智能的人工智能
- 在瘤学瘤学.
背景情况:
- 乳腺癌 (BC) 是全球女性癌症死亡的主要原因.
- 转移到状淋巴结 (ALN) 显著降低了BC患者的存活率.
- 目前用于检测ALN转移的成像方法缺乏灵敏度和可访问性.
研究的目的:
- 开发和验证基于AI的红外热像系统,用于检测乳腺癌中的ALN转移.
- 改善诊断的可访问性和减少与干预ALN转移相关的发病率.
主要方法:
- 使用北京联合医学院医院的内部队列 (460名患者) 开发了一种深度学习模型.
- 该模型对70%的内部队列进行了培训,并对剩余的30%进行了验证.
- 独立验证是在长福医院的80名患者的外部队列上进行的.
主要成果:
- 在内部验证中,AI-IRT模型实现了0.9424的AUC和84.78%的准确性.
- 内部验证显示灵敏度为89.58%,特异性为82.22%.
- 外部验证显示AUC的准确度为0.881和87.5%,灵敏度为89.2%,特异性为86.1%.
结论:
- 在多个中心,AI-IRT系统表现出强大的诊断性能.
- 人工智能IRT系统有可能提高乳腺癌患者的术前和术后决策能力.
- 这种基于人工智能的方法为ALN转移检测提供了更好的可访问性.
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