时代型,生活方式以及心血管风险评估中肥胖个体的人类指数和生物化学指数
Margarida Rabaça Alexandre1, Rui Poínhos1,2, Cri-O Group3
1Faculty of Nutrition and Food Sciences, University of Porto, 4150-180 Porto, Portugal.
Nutrients
|June 13, 2025
概括
男性的性别,晚间时间型和睡眠质量差与肥胖个体的心脏代谢健康状况恶化有关. 整合行为和昼夜因素可以改善严重肥胖的心血管风险评估.
科学领域:
- 心脏病学 心脏病学
- 代谢健康 代谢健康
- 行为科学 行为科学
背景情况:
- 肥胖显著导致心血管疾病 (CVD).
- 传统的心血管疾病风险评估可能无法完全捕捉行为和昼夜节律对代谢健康的影响.
- 时间型,体力活动,睡眠,进食速度和早餐习惯等因素越来越多地与心脏代谢结果有关.
研究的目的:
- 调查行为和昼夜因素与心血管风险的人类测量/生化标志物之间的联系.
- 评估在接受减肥手术评估的肥胖个体中评估这些关联.
主要方法:
- 这是一项对286名肥胖成年人 (平均BMI为42.5kg/m2) 的横截面研究.
- 评估时间型,睡眠质量 (匹兹堡睡眠质量指数),身体活动,进食速度和跳过早餐.
- 测量了心血管风险标志物,包括腰比 (WHR),身体形状指数 (ABSI),血动脉生成指数 (AIP),甘油三糖指数 (TyG) 和HOMA-IR.
主要成果:
- 男性的WHR,ABSI,HOMA-IR,TyG和AIP都较高.
- 晚间时间型与更高的胰岛素和HOMA-IR相关.
- 睡眠质量不佳与增加体脂量,总胆固醇和LDL胆固醇有关.
- 更快的进食速度与更大的腰围和更大的骨肌肉质量有关.
结论:
- 男人性别,晚间时间型和睡眠质量差与严重肥胖症的不良心脏代谢特征有关.
- 这些行为和昼夜因素是评估心血管风险的重要考虑因素.
- 研究结果支持将这些要素纳入综合性风险评估策略.
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